Bone Grafting for Nonunion

When a bone fracture fails to heal properly, it’s referred to as a nonunion. This can occur when the bone doesn’t fuse back together despite treatment, leaving patients with persistent pain and disability. One of the most common bones affected by nonunions is the tibia, or shin bone. Nonunions in the tibia are especially problematic because of the bone’s role in weight-bearing and mobility. Treating these nonunions involves different surgical techniques, and one of the more promising methods is bone grafting.

What Is Bone Grafting?

Bone grafting involves taking bone tissue from one part of the body (typically from the iliac crest, the top of the pelvic bone) and transplanting it to the nonunion site. This helps stimulate healing by providing a scaffold for new bone growth. Bone grafting is a key treatment option when fractures fail to heal on their own, especially in complex cases.

The Central Bone Grafting Technique

Central bone grafting is a surgical technique that has been found to be very effective in treating difficult tibial nonunions. This method involves creating a space in the tibia (the shin bone) and filling it with bone graft material. Here’s how it works:

  1. Surgical Approach: The surgeon makes an incision just in front of the fibula (the smaller bone next to the tibia) and carefully exposes the tibia. The fibula and surrounding tissues are moved aside to create space in the tibia.
  2. Bone Graft Placement: Cancellous bone (the spongy, softer bone found in the iliac crest) is harvested and placed into the gap created in the tibia. This bone graft serves as a foundation for new bone growth, encouraging the fractured tibia to heal.
  3. Healing and Weight-Bearing: Over time, the bone graft fuses with the tibia, allowing the bone to heal completely. In many cases, patients are able to bear weight on the leg once the fracture has healed, often within about 20 weeks.

Advantages of Central Bone Grafting

Central bone grafting has several advantages over other methods:

  • Effective for Complex Cases: It’s particularly useful for tibial fractures with associated bone loss, infection, or damage to the bone’s blood supply.
  • Faster Healing: In studies, patients who received central bone grafting healed more quickly, with a mean healing time of 20 weeks compared to 31 weeks for other grafting methods.
  • Lower Complication Rate: This method has fewer complications, and most patients avoid needing additional surgeries.

When Is Central Bone Grafting Used?

Central bone grafting is recommended for nonunions that involve:

  • Bone Loss: When a significant portion of the bone is missing due to the fracture.
  • Infection: If there’s been an infection at the fracture site that interferes with healing.
  • Failure of Other Treatments: For cases where simpler treatments (like casts or rods) haven’t worked.

The Procedure: Step by Step

Here’s a basic overview of the central bone grafting procedure:

  1. Pre-Op Preparation: The patient is placed under general anesthesia and positioned on the operating table. The area around the tibia and iliac crest (for the bone graft) is cleaned and sterilized.
  2. Incision: The surgeon makes a cut just in front of the fibula and exposes the tibia. The muscle and tissue around the tibia are moved to create space for the graft.
  3. Bone Harvesting: A portion of bone is taken from the iliac crest. The surgeon makes a small cut in the pelvic bone to retrieve cancellous bone.
  4. Bone Graft Insertion: The harvested bone is placed into the gap in the tibia. This space is carefully packed with the bone graft material to promote healing.
  5. Closure: After placing the graft, the surgeon will close the incisions with stitches. The patient may need to wear a cast or undergo further stabilization, depending on the severity of the nonunion.

Post-Operative Care and Recovery

After surgery, the patient will need to follow specific care instructions to ensure proper healing:

  • Weight-Bearing: Most patients will be advised to avoid putting weight on the leg until the fracture is fully healed.
  • Physical Therapy: Once the bone has healed sufficiently, physical therapy may be required to regain strength and mobility in the leg.
  • Follow-Up Appointments: Regular follow-up visits are necessary to monitor the healing process through X-rays and clinical exams.

Results and Success Rate

Central bone grafting is a highly successful treatment, with most patients achieving full union of their tibial fractures within a few months. In studies, about 95% of patients who underwent this procedure showed complete healing, and the risk of further complications was minimal.

Complications

As with any surgery, there are risks involved, but complications are rare with central bone grafting. Some potential issues include:

  • Infection: Although infection rates are low, it’s always a concern in bone-related surgeries.
  • Pain at the Graft Site: Some patients may experience discomfort at the site where the bone was harvested (the iliac crest).
  • Delayed Healing: In some cases, it may take longer than expected for the bone to heal.

Conclusion

Bone grafting for tibial nonunions, particularly central bone grafting, is an effective treatment option for patients with complex fractures. By carefully addressing issues such as bone loss and infection, this technique can promote healing and restore function to the leg, allowing patients to return to an active lifestyle.

If you or a loved one is dealing with a nonunion fracture, consult an orthopedic surgeon to discuss whether central bone grafting might be the right solution for you.

 

Do you have more questions?

Q. What is Bone Grafting for Nonunion?
A. Bone grafting for nonunion involves transplanting bone tissue to the site of a nonunion (a fracture that has not healed properly) to stimulate healing and promote bone growth, often using bone from the iliac crest or synthetic graft material.

Q. What is the central bone grafting technique?
A. Central bone grafting is a specific technique used to treat difficult tibial nonunions. It involves creating a space in the tibia and filling it with bone graft material to stimulate healing.

Q. When is Bone Grafting used for Nonunion?
A. Bone grafting is used when a fracture fails to heal after standard treatments, especially in cases with bone loss, infection, or compromised blood supply that prevent the bones from fusing naturally.

Q. What is the recovery time for bone grafting surgery for nonunion?
A. Recovery typically involves several weeks of immobilization, with most patients able to bear weight on the leg once the fracture heals. Full recovery may take up to 20 weeks.

Q. What are the risks of bone grafting for nonunion?
A. Risks include infection, delayed union, pain at the graft site, failure of the bone to heal properly, and complications related to the donor site, especially if the iliac crest is used for harvesting the graft.

Q. How long does the Bone Grafting for Nonunion procedure take?
A. The surgery typically takes 2 to 3 hours, depending on the complexity of the nonunion and whether additional procedures, such as hardware placement or infection management, are needed.

Q. What is the success rate of Bone Grafting for Nonunion?
A. The success rate for bone grafting in nonunion cases is high, with approximately 95% of patients experiencing full healing of the fracture. The success largely depends on the patient’s overall health and adherence to rehabilitation protocols.

Q. Can bone grafting for nonunion be combined with other treatments?
A. Yes, bone grafting can be combined with other treatments, such as internal fixation (using screws or plates), to enhance the stability and healing process of the fractured bone.

Q. What are the types of bone grafts used in nonunion surgery?
A. The types of bone grafts include autografts (bone taken from the patient’s own body, typically from the iliac crest), allografts (bone from a donor), and synthetic or bioengineered grafts. Autografts are preferred for their higher success rates, but allografts and synthetic options are used in certain cases.

Q. What is the difference between an autograft and an allograft?
A. An autograft is bone taken from the patient’s own body, which reduces the risk of rejection but involves an additional surgical site. An allograft is bone taken from a donor, which avoids an additional incision but carries a slight risk of disease transmission and may have a higher failure rate.

Q. Can bone grafting for nonunion be performed minimally invasively?
A. In some cases, minimally invasive techniques may be used for bone grafting, depending on the location of the nonunion. However, traditional open surgery is often required for better access to the fracture site and for proper placement of the graft.

Q. Will I need to use crutches or a walker after bone grafting surgery for nonunion?
A. Yes, crutches, a walker, or a brace are typically needed to avoid putting weight on the operated leg during the initial recovery period, usually for 6 to 8 weeks, depending on the healing progress.

Q. How long will the bone graft material take to fully integrate into the bone?
A. Full integration of the bone graft typically takes several months. The graft will begin to fuse with the existing bone, and the patient will be monitored through follow-up appointments to ensure proper healing and graft acceptance.

Q. Will physical therapy be needed after bone grafting for nonunion?
A. Yes, physical therapy is an important part of recovery. It helps restore strength, flexibility, and mobility to the affected area once the bone has healed sufficiently. Rehabilitation usually starts after the initial healing phase.

Q. What can I do to ensure the success of bone grafting for nonunion?
A. Following post-surgical instructions, attending follow-up appointments, avoiding weight-bearing activities as instructed, and maintaining a healthy diet with adequate calcium and vitamin D intake are crucial for the success of the procedure.

Q. Can smoking affect the success of bone grafting for nonunion?
A. Yes, smoking can significantly impair the healing process by reducing blood flow to the bones and tissues, which may increase the risk of graft failure. It is strongly recommended to quit smoking before and after surgery to improve the chances of successful healing.

Dr. Mo Athar
Dr. Mo Athar
A seasoned orthopedic surgeon and foot and ankle specialist, Dr. Mohammad Athar welcomes patients at the offices of Complete Orthopedics in Queens / Long Island. Fellowship trained in both hip and knee reconstruction, Dr. Athar has extensive expertise in both total hip replacements and total knee replacements for arthritis of the hip and knee, respectively. As an orthopedic surgeon, he also performs surgery to treat meniscal tears, cartilage injuries, and fractures. He is certified for robotics assisted hip and knee replacements, and well versed in cutting-edge cartilage replacement techniques.
In addition, Dr. Athar is a fellowship-trained foot and ankle specialist, which has allowed him to accrue a vast experience in foot and ankle surgery, including ankle replacement, new cartilage replacement techniques, and minimally invasive foot surgery. In this role, he performs surgery to treat ankle arthritis, foot deformity, bunions, diabetic foot complications, toe deformity, and fractures of the lower extremities. Dr. Athar is adept at non-surgical treatment of musculoskeletal conditions in the upper and lower extremities such as braces, medication, orthotics, or injections to treat the above-mentioned conditions.